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Tuberculosis Innovation

…ity also houses a program that helps to test anti-tuberculosis compounds for other laboratories around the world. For the first time in years, scientists are making significant advancements that may help in the fight against tuberculosis. Some of the tuberculosis vaccines and drugs that have been tested at CSU are now in clinical trials in South Africa, and the university continues to make meaningful discoveries in basic research to understand…

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High-school students get hands-on experience with tuberculosis research

…Laboratories for about 80 students from science classes at Fort Collins high schools. The students visited labs on the Foothills Campus to mark World TB Day, which annually raises awareness about the infectious lung disease tuberculosis and its devastating global impact. Visiting students got a lab-level look at cutting-edge research to better understand, detect, prevent and cure TB. The respiratory disease, caused by Mycobacterium…

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Team lands NIH funds to examine tuberculosis and metabolism

…ding to the World Health Organization. In 2013, an estimated 9 million people became ill with TB and 1.5 million died from the disease. The TBRU in which CSU is involved, “Metabolic Factors that Control the Spectrum of Human Tuberculosis,” is expected to receive up to $19.5 million over seven years. The unit will examine how the chronic bacterial infection changes metabolism and why altered metabolism increases TB disease susceptibility….

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CSU study offers new recommendations for TB vaccine testing in humans

…t of the vaccines out there use laboratory strains in testing. Ian has led the field to push for testing clinical strains.” The study, “The efficacy of the BCG vaccine against newly emerging clinical strains of Mycobacterium tuberculosis,” was published in September. Learn more about CSU’s tuberculosis research and the scientists looking for new ways to test for TB, new drugs to treat it, and vaccines to prevent tuberculosis before or…

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Immunology professor lands national honor for TB research

…rch Laboratories, which has grown to include more than 150 research personnel. It is located in one of the most secure laboratories of its kind in the world, where researchers can work with some of the most virulent types of tuberculosis. “With over 2 billion people infected with M. tuberculosis worldwide, the current and future potential impact of Dr. Orme’s work is truly impressive,” AAAS Fellow Jeffrey Wilusz, one of Orme’s fellow professors…

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Students compete with research in health, medicine

…professor of mycobacterial pathology The infectious disease tuberculosis is a leading cause of death around the world. Joen aims to use small molecule compound adjuvants to overcome the antibiotic resistance of Mycobacterium tuberculosis. The approach could boost immunity and improve therapeutic strategies for tuberculosis patients. “Research fulfills my passion to discover unknown things about infectious disease and provides me with a valuable…

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Breakthrough imaging tool maps cells’ composition in 3-D

…h an interdisciplinary group of faculty, devised and built the instrument with help from students. She found a partner in CSU’s renowned Mycobacteria Research Laboratories, which seek new treatments for the global scourge of tuberculosis. The partners described the system in a paper published earlier this year in Nature Communications. Unprecedented detail Dean Crick, a professor who researches tuberculosis, collaborated with Menoni to refine…

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From the bench: Grad students win for research into HIV, prions, reproduction and more

…roject: Immune Response Against Mycobacterium Tuberculosis after Acquisition of Isoniazid Resistance Description: Virulence, pathology and immune response of the TB bacterium. “My work is focused on the bacterium that causes tuberculosis and its resistance to one specific drug called isoniazid. I studied what happens to the tuberculosis bacterium when it becomes drug-resistant.” Award: CVMBS Best Poster by a PhD or MS-Thesis Researcher Mentor:…

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Undergrads find best fit in labs with fellowships

…of Angelo Izzo, associate professor of mycobacterial immunology, and had managed one research project, examining the types of bacteria at different work stations. The Izzo lab conducts research on potential new vaccines for tuberculosis. MIP Undergraduate Research Fellow Cassidy Hagan is doing tuberculosis research in Angelo Izzo’s lab. Now, thanks to the fellowship, Hagan said she will examine the the immune response induced by different…

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Professors recognized for fostering Colorado children

…gy, Immunology, and Pathology. Podell’s laboratory focuses on autoimmunity and infectious disease, with an emphasis on diabetes and tuberculosis. His research aims to discover new ways to prevent and treat diabetes and tuberculosis, especially when the two diseases occur together, a comorbidity of emerging importance in countries where tuberculosis is endemic. Interested in learning more about being a foster parent? The state’s…

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